Heating Causes a Rise in the Concentration of Intracellular Sodium in Human Cells in Vitro
نویسندگان
چکیده
A rise in intracellular sodium ion concentration ([Na+]i) was predicted by Hubbard in his "energy depletion mechanism" of heatstroke [ l ] but such rises have not been clearly shown. In this study, we have found rises in [Na+]i at elevated temperatures in isolated human squamous epithelial cells, by measuring changes in the fluorescence of a Na+-sensitive fluorophore which had been introduced into those cells.
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